Definition and contrast osteoporosis and osteomalacia. Both osteoporosis and osteomalacia can lead to a decrease in bone strength. In osteoporosis, the bone mass decreases with the normal treatment of the mineral matrix. In osteomalacia, mineral matrix ratio decreases. Osteoporosis reduces bone mass, with normal treatment of bone matrix in addition to altered microarchitecture of bone tissue. Osteoporosis
phrase "normal enough bones, but not enough!"
Clinical manifestations of osteoporosis include fractures from minimal trauma, especially in the thoracic and lumbar spine, wrist and hip. Thoracic vertebral compression fractures can lead to spinal kyphosis (widow's hump). Plain X-rays show decreased bone density, but only once, at least 30% bone loss. Dual energy x-ray absorptimoetry (DEXA) is a diagnostic test for the treatment of osteoporosis, according to bone density in terms of evaluation of T, representing the deviation from the average normal person). DEXA 2. 5 diagnosis of osteoporosis. Laboratory values of serum calcium phosphates, phosphorus and alakaline lasix drug dose is not diagnostic. Osteomalacia is characterized by the decrease of bone in the matrix. (Osteomalacia when it appears in children is called rickets "). Histologic study of non-mineralized osteoida looks like a thickened layer matrix.
The disease is characterized by symptoms of diffuse pain in the bones, pain and muscle weakness. X-rays usually show decreased bone density thinning of the cerebral cortex. Advanced disease may lead to the concavity of the vertebral bodies (cod vertebrae) and curved legs. In addition, cracks (so called loser in zones) may seem. These incomplete fractures filled with non-mineralized osteoida seams. Laboratory results may show low serum and urine calcium and high serum alkaline phosphate. / ** /.
No comments:
Post a Comment